Casualties have been reported after an Amazon Boeing 767 jet smashed into a road just outside Miami International Airport.

Firefighters report that the cargo plane struck several vehicles after veering off the runway.

At least five people died and five were injured,mayor Daniella Levine confirmed.

Footage showed the huge cargo plane blocking traffic while huge plumes of black smoke billowed up from the wreckage on Sunday.

Smoke billows from the crash at Miami International Airport where the Amazon jet collided on the runway (Picture: AP)

Mayor Levine described it as a ‘very difficult day’. She told reporters: ‘We can confirm that we have at least five deceased individuals.

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Start your day informed with Metro's News Updates newsletter or get Breaking News alerts the moment it happens.‘Multiple individuals were transported to local hospitals with unknown injuries.’The delivery plane was headed to Miami from San Juan,Puerto Rico and crashed near an Amazon warehouse.WATCH: Moments after a Prime Air Boeing 767 overshot the runway at Miami International Airport and crossed a road pic.twitter.com/kyCeeOpHdp— BNO News (@BNONews) September 6,2026It is not clear what caused the crash.Data from tracking website Flightradar24 shows the plane was travelling at around 128 mph when it veered off the runway,according to ABC News.The FAA said: ’21 Air Flight 7598 overran the runway after landing at Miami International Airport around 2pm local time.‘The Boeing 767-300 cargo aircraft departed from Luis Muñoz Marín International Airport in San Juan,Puerto Rico. The FAA will investigate.’The Amazon Prime Air cargo plane that airport officials said overran a runway at Miami International Airport (Picture: REUTERS)Kelly Nantel,a spokesperson for Amazon,said in a statement: ‘We’re heartbroken to learn that five people lost their lives in today’s incident at Miami International Airport.‘Our deepest sympathies go out to the families,loved ones,and all those affected by this devastating loss.‘The airplane,which was operated by 21 Air,was attempting to land when this incident occurred. We’re working closely with local authorities and officials to learn more and will cooperate fully with any investigation.’Get in touch with our news team by emailing us at .For more stories like this,check our news page.